Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements.

Histochemistry and cell biology2011Rybaczek D, Kowalewicz-Kulbat M

Study designOther primary literature

SubjectHuman

Abstract

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MeSH

2-AminopurineCaffeineCheckpoint Kinase 1Chromosomes, HumanCytoskeletonHela CellsHistonesHumansPhosphorylationProtein KinasesS PhaseStaurosporineStructure-Activity RelationshipVanadates

DOI 10.1007/s00418-011-0793-3

PMID 21347609

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