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Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium.

The journal of headache and pain2008Pini LA, Del Bene E, Zanchin G, et al.
Study designRandomized controlled trial
SubjectHuman

Abstract

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MeSH

AcetaminophenAdolescentAdultAgedAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalCaffeineCentral Nervous System StimulantsCross-Over StudiesDouble-Blind MethodDrug EvaluationDrug Therapy, CombinationFemaleHumansItalyMaleMiddle AgedNaproxenPain MeasurementPain ThresholdRetrospective StudiesTension-Type HeadacheYoung Adult

DOI 10.1007/s10194-008-0071-5

PMID 18815727

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