Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress.

Biochimica et biophysica acta. Molecular basis of disease2024Lu Z, Sun GF, He KY, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

Amino Acids, Branched-ChainAnimalsApoptosisCell Line, TumorGTP PhosphohydrolasesGlioblastomaHumansMaleMiceMitochondrial ProteinsOxidative StressReactive Oxygen SpeciesSignal TransductionUbiquitinUbiquitination

DOI 10.1016/j.bbadis.2024.167220

PMID 38718847

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