Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels.

Alzheimer's & dementia : the journal of the Alzheimer's Association2016Ruiz HH, Chi T, Shin AC, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

Alzheimer DiseaseAmino Acids, Branched-ChainAmyloid beta-Protein PrecursorAnimalsBody WeightDiet, High-FatDisease Models, AnimalEatingGene Expression RegulationHumansHypothalamusInsulinInsulin ResistanceMaleMetabolic DiseasesMiceMice, TransgenicMutationPresenilin-1Signal TransductionTriglycerides

DOI 10.1016/j.jalz.2016.01.008

PMID 26928090

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