Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR-CaMKII-ERK/CREB signalling on consumption of aspartame in rat model.
Journal of food and drug analysis2018Iyaswamy A, Kammella AK, Thavasimuthu C, et al.
Study designOther primary literature
SubjectAnimal
Abstract
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MeSH
AnimalsApoptosisAspartameBrainCalcium-Calmodulin-Dependent Protein Kinase Type 2Cyclic AMP Response Element-Binding ProteinExtracellular Signal-Regulated MAP KinasesFemaleMaleMemoryMethanolNitric OxideNitric Oxide Synthase Type INitric Oxide Synthase Type IIOxidative StressRatsRats, WistarReceptors, N-Methyl-D-AspartateSignal TransductionSweetening Agents