Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism.

Molecular metabolism2023Ferguson D, Eichler SJ, Yiew NKH, et al.

Study designRandomized controlled trial

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)Amino Acids, Branched-ChainAnimalsCarcinoma, HepatocellularDiabetes Mellitus, Type 2GlucoseHumansInsulin ResistanceLiver NeoplasmsMiceMonocarboxylic Acid TransportersNon-alcoholic Fatty Liver DiseaseRatsRats, ZuckerSpiro CompoundsTOR Serine-Threonine Kinases

DOI 10.1016/j.molmet.2023.101694

PMID 36801448

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