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Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").

Neuropharmacology2006McNamara R, Kerans A, O'Neill B, et al.
Study designOther primary literature
SubjectAnimal

Abstract

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MeSH

3,4-MethylenedioxyamphetamineAnimalsArea Under CurveBehavior, AnimalBody TemperatureBrain ChemistryCaffeineCentral Nervous System StimulantsDose-Response Relationship, DrugDrug SynergismDrug ToleranceFeverHallucinogensHydroxyindoleacetic AcidMaleMotor ActivityN-Methyl-3,4-methylenedioxyamphetamineRatsRats, Sprague-DawleySeizuresSerotonin

DOI 10.1016/j.neuropharm.2005.08.006

PMID 16188283

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