Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation.

Toxicology letters2012Tan Y, Liu J, Deng Y, et al.

Study designOther primary literature

SubjectAnimal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AnimalsCaffeineCentral Nervous System StimulantsFemaleFemurFetal DevelopmentFetal Growth RetardationFetal WeightGene Expression Regulation, DevelopmentalGlucocorticoidsGrowth PlateHistonesInsulin-Like Growth Factor ILiverMaleMaternal ExposureMaternal-Fetal ExchangeMethylationPregnancyRNA, MessengerRatsRats, Wistar

DOI 10.1016/j.toxlet.2012.09.007

PMID 22995397

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