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Caffeine increases performance and leads to a cardioprotective effect during intense exercise in cyclists.

Scientific reports2021Sampaio-Jorge F, Morales AP, Pereira R, et al.
Study designRandomized controlled trial
SubjectHuman

Abstract

The present study was designed to investigate the effects of different caffeine dietary strategies to compare the impact on athletic performance and cardiac autonomic response. The order of the supplementation was randomly assigned: placebo(4-day)-placebo(acute)/PP, placebo(4-day)-caffeine(acute)/PC and caffeine(4-day)-caffeine(acute)/CC. Fourteen male recreationally-trained cyclists ingested capsules containing either placebo or caffeine (6 mg kg-1) for 4 days. On day 5 (acute), capsules containing placebo or caffeine (6 mg kg-1) were ingested 60 min before completing a 16 km time-trial (simulated cycling). CC and PC showed improvements in time (CC vs PP, Δ - 39.3 s and PC vs PP, Δ - 43.4 s; P = 0.00; ƞ2 = 0.33) and in output power (CC vs PP, Δ 5.55 w and PC vs PP, Δ 6.17 w; P = 0.00; ƞ2 = 0.30). At the final of the time-trial, CC and PC exhibited greater parasympathetic modulation (vagal tone) when compared to the PP condition (P < 0.00; ƞ2 = 0.92). Our study provided evidence that acute caffeine intake (6 mg∙kg-1) increased performance (time-trial) and demonstrated a relevant cardioprotective effect, through increased vagal tone.

MeSH

AdultAthletic PerformanceBicyclingCaffeineCardiotonic AgentsCentral Nervous System StimulantsCross-Over StudiesDouble-Blind MethodExerciseHeart RateHumansMaleOxygen Consumption

DOI 10.1038/s41598-021-03158-2

PMID 34934054

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