Fluvoxamine impairs single-dose caffeine clearance without altering caffeine pharmacodynamics.
British journal of clinical pharmacology2005Culm-Merdek KE, von Moltke LL, Harmatz JS, et al.
Study designRandomized controlled trial
SubjectHuman
Abstract
cc by 以外(cc by-nc / cc by-nc-nd / NONE 等)は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。
MeSH
Area Under CurveCaffeineCentral Nervous System StimulantsChromatography, High Pressure LiquidCross-Over StudiesDouble-Blind MethodDrug CombinationsDrug InteractionsElectroencephalographyFemaleFluvoxamineHalf-LifeHumansMaleMiddle AgedPsychomotor PerformanceSelective Serotonin Reuptake Inhibitors