Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects.

British journal of clinical pharmacology2006Backman JT, Karjalainen MJ, Neuvonen M, et al.

Study designRandomized controlled trial

SubjectHuman

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AdultCaffeineCentral Nervous System StimulantsClonidineCyclooxygenase 2 InhibitorsCytochrome P-450 CYP1A2 InhibitorsDouble-Blind MethodDrug InteractionsHumansLactonesMaleSulfones

DOI 10.1111/j.1365-2125.2006.02653.x

PMID 16934051

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