Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain.

Journal of neurochemistry2020Ganesan D, Ramaian Santhaseela A, Rajasekaran S, et al.

Study designOther primary literature

SubjectAnimal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AgingAmino Acids, Branched-ChainAnimalsAstrocytesAutophagyBiotinBrainEndoplasmic Reticulum StressGlial Fibrillary Acidic ProteinLipid MetabolismLipogenesisMechanistic Target of Rapamycin Complex 1Rats, Wistar

DOI 10.1111/jnc.14979

PMID 32030764

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