Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design.

Molecular cancer therapeutics2016Dorywalska M, Dushin R, Moine L, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AnimalsAntibodies, MonoclonalAntineoplastic AgentsBiomarkersCarbamatesCarboxylesteraseCitrullineDrug DesignDrug StabilityHumansImmunoconjugatesMiceMice, KnockoutModels, MolecularMolecular ConformationMolecular StructureProtein BindingStructure-Activity RelationshipValine

DOI 10.1158/1535-7163.mct-15-1004

PMID 26944918

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