Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.
The Journal of neuroscience : the official journal of the Society for Neuroscience2011Lazarus M, Shen HY, Cherasse Y, et al.
Study designOther primary literature
SubjectHuman & animal
Abstract
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MeSH
Analysis of VarianceAnimalsArousalBasal GangliaCaffeineCell Line, TransformedCentral Nervous System StimulantsCholine O-AcetyltransferaseDose-Response Relationship, DrugElectroencephalographyElectromyographyGreen Fluorescent ProteinsHumansLocomotionMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMutagenesisMutationNucleus AccumbensPhosphopyruvate HydrataseRNA, Small InterferingRatsRats, Sprague-DawleyReceptor, Adenosine A2AReceptors, Dopamine D2Transfection