Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.
Journal of Alzheimer's disease : JAD2009Cao C, Cirrito JR, Lin X, et al.
Study designOther primary literature
SubjectHuman & animal
Abstract
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MeSH
Age FactorsAlzheimer DiseaseAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnalysis of VarianceAnimalsBrainCaffeineCentral Nervous System StimulantsCognitionCytokinesDisease Models, AnimalDose-Response Relationship, DrugDrug Administration ScheduleHumansMaze LearningMiceMice, TransgenicMicrodialysisPhosphodiesterase InhibitorsPlasmaPresenilin-1TheophyllineTime Factors