TIPE2 gene transfer ameliorates aging-associated osteoarthritis in a progeria mouse model by reducing inflammation and cellular senescence.

Molecular therapy : the journal of the American Society of Gene Therapy2024Guo P, Gao X, Nelson AL, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AgingAnimalsCartilage, ArticularCellular SenescenceChondrocytesDependovirusDisease Models, AnimalGene Transfer TechniquesGenetic TherapyGenetic VectorsHumansInflammationIntracellular Signaling Peptides and ProteinsMiceMice, KnockoutOsteoarthritisProgeriaTumor Necrosis Factor-alpha

DOI 10.1016/j.ymthe.2024.07.027

PMID 39095992

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