Aspartame exacerbates cerebral ischemia-reperfusion injury via mitochondrial dysfunction and ERK/CREB1 pathway suppression.
Ecotoxicology and environmental safety2026Bai Y, Feng J, Wu XY, et al.
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MeSH
AnimalsApoptosisAspartameBrain IschemiaCyclic AMP Response Element-Binding ProteinMAP Kinase Signaling SystemMaleMiceMice, Inbred C57BLMitochondriaNeural Stem CellsReactive Oxygen SpeciesReperfusion InjurySignal TransductionSweetening Agents
DOI 10.1016/j.ecoenv.2026.119938
PMID 41762991
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