A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine.
Neurotoxicology2008van Vliet E, Morath S, Eskes C, et al.
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MeSH
AnimalsCaffeineCell SurvivalCells, CulturedCentral Nervous System StimulantsCholineCreatineDose-Response Relationship, DrugEmbryo, MammalianGlutamineKidneyL-Lactate DehydrogenaseLiverMercuric ChlorideNeuronsNeurotoxinsPrincipal Component AnalysisRatsSpermineTandem Mass SpectrometryTelencephalongamma-Aminobutyric Acid
DOI 10.1016/j.neuro.2007.09.007
PMID 18023877
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