Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation.
Toxicology letters2012Tan Y, Liu J, Deng Y, et al.
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MeSH
AnimalsCaffeineCentral Nervous System StimulantsFemaleFemurFetal DevelopmentFetal Growth RetardationFetal WeightGene Expression Regulation, DevelopmentalGlucocorticoidsGrowth PlateHistonesInsulin-Like Growth Factor ILiverMaleMaternal ExposureMaternal-Fetal ExchangeMethylationPregnancyRNA, MessengerRatsRats, Wistar
DOI 10.1016/j.toxlet.2012.09.007
PMID 22995397
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