BCAT1-elicited branched-chain amino acid catabolism fosters neutrophil-mediated pan-metastasis in pancreatic cancer.
Molecular therapy : the journal of the American Society of Gene Therapy2026Xie F, Ren YZ, Jian ZW, et al.
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MeSH
Amino Acids, Branched-ChainAnimalsCarcinoma, Pancreatic DuctalCell Line, TumorGene Expression Regulation, NeoplasticHumansMetabolic ReprogrammingMiceNeoplasm MetastasisNeutrophilsPancreatic NeoplasmsSignal TransductionTOR Serine-Threonine KinasesTransaminasesTumor Microenvironment
DOI 10.1016/j.ymthe.2026.01.039
PMID 41635084
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