Dietary intake and BCAA metabolism regulate pulmonary fibrosis through KDM4A-mediated epigenetic remodeling in male mice.
Nature communications2026Yao J, Fang S, Lei M, et al.
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MeSH
Activating Transcription Factor 4Amino Acids, Branched-ChainAnimalsBleomycinDietDisease Models, AnimalEpigenesis, GeneticFibroblastsHumansIdiopathic Pulmonary FibrosisJumonji Domain-Containing Histone DemethylasesLungMaleMiceMice, Inbred C57BLPPAR gammaPulmonary FibrosisTransaminases
DOI 10.1038/s41467-026-72273-3
PMID 42045225
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