The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study.

Cephalalgia : an international journal of headache2005Diener HC, Pfaffenrath V, Pageler L, et al.

研究デザインランダム化比較試験

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MeSH

AcetaminophenAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalAspirinCaffeineDouble-Blind MethodDrug Administration ScheduleDrug CombinationsDrug SynergismGermanyHumansMigraine DisordersPain MeasurementPlacebo EffectPrognosisSeverity of Illness IndexTension-Type HeadacheTreatment Outcome

DOI 10.1111/j.1468-2982.2005.00948.x

PMID 16162254

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